secondary (after the primary indefinite disease Budd-Chiari) violation of the outflow of blood from the liver associated with some pathologies that are not associated with changes in the blood vessels of the body.
Causes and prevalence of Budd-Chiari
The Budd-Chiari observed in the peritonitis, pericarditis, tumors of the abdominal cavity, malformations of the inferior Vena cava thrombosis, cirrhosis, and focal lesions of the liver, with polycythemia and migratory thrombophlebitis (visceral).
Disease and Budd-Chiari occurs with a frequency of 13-31% of all cases of thrombosis.
Symptoms of Budd-Chiari
Depending on the nature of development, distinguish acute, subacute and chronic phase
- the acute phase is characterized by the appearance of intense pain in the right hypochondrium, enlargement of the liver, vomiting. If the process involved the inferior Vena cava, there may be leg swelling, and dilatation of subcutaneous veins of the chest and abdominal wall. Progress is pretty intense for a few days, ascites develops, in most cases with hemorrhagic in nature
- the chronic form is characterized by a long asymptomatic course of endofinite. Further symptoms may occur pain in the right hypochondrium, vomiting. The liver is increased, the density of the body increases. Is not excluded the formation of cirrhosis, sometimes there are dilated veins on the chest and anterior abdominal wall. The outcome of the disease in the chronic form severe liver failure.
Diagnosis of the syndrome is quite complicated. The assumption that the disease usually arises in the study of history and detection from patient’s ascites hepatomegaly especially if there are irregularities in the blood coagulation system. The most reliable diagnostic data enables angiography and hematobilia.
Treatment of Budd-Chiari
If hepatic failure is absent, appoint surgical treatment (overlay anastomosis). In the management of refractory ascites are shown lymphovenous anastomosis. Apply and other methodologies, depending on the overall condition and functionality of the body. To fully restore the functional state of the liver will only transplantation.
The effectiveness of conservative therapy is very low with it only to achieve a temporary symptomatic effect. Mortality in the treatment without surgical intervention up to 90%.
Correctly diagnosing the Budd-Chiari and identify it at early stages can professional gastroenterologist. To find the best candidate, and to pick up a diagnostic laboratory for proper diagnosis of the disease is possible via the website Doc.ua.