1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)

Syndrome Waterhouse-Friderichsen

  1. Reasons
  2. Symptoms
  3. Diagnosis
  4. Treatment

Syndrome Waterhouse-Friderichsen

a disease in which the refuse of the function of the adrenal cortex, resulting in problems in the process of blood circulation, neurological disruptions, disruption of water and electrolyte metabolism.

This syndrome can occur regardless of gender and age.


Can often see the syndrome Waterhouse-Friderichsen in children, because there is a great probability to get it at birth due to a difficult birth that led to profuse hemorrhage in the adrenal cortex, which becomes a reason for further development of the syndrome.

Also acute adrenal insufficiency can be caused by infectious diseases such as




Violations of the complex exchange of blood and burns no less than weak stimuli, leading to the disease.

Syndrome Waterhouse-Friderichsen often appears after surgery to remove a tumor of the adrenal cortex, which leads to its defective functioning.


A simple man will not be able to identify independently the adrenal insufficiency, because the full detection of the disease requires special tests.

This disease develops very quickly, and with no less speed and in humans with healthy bodies, picked up any infection.

Syndrome Waterhouse-Friderichsen never leak on their own, his symptoms associated with another disease, which led to the dysfunction of the adrenal cortex.

There are several types of disease depending on the primary lesion is gastrointestinal, cardiovascular, meningoencephalitic, misc.

The gastrointestinal form of the disease has the main symptoms

  • quick dehydration
  • sharp pain in the abdomen
  • diarrhea
  • cold sweat
  • nausea, vomiting
  • flatulence.

About cardiovascular form of report

  • poor circulation with cyanosis
  • cold sweat
  • thready pulse
  • tachycardia.

A severe form of the disease is a meningo-encephalic, accompany her

  • nonsense
  • dizziness
  • convulsions.

The most common form of the disease combined. Her symptoms

  • a drop in blood pressure
  • high body temperature
  • chills
  • collapse
  • cyanosis
  • rash on belly and chest.

These symptoms of acute adrenal insufficiency is not limited, therefore, to prevent complications and surgery is the manifestation of similar or other symptoms go to the hospital.


In acute insufficiency of the adrenal cortex hardware diagnostics the best way to detect the disease, because the symptoms of different forms of the syndrome Waterhouse-Friderichsen similar with other diseases, such as, for example

hemorrhage into the brain or stomach ulcers.

To identify the disease will help you efficiently collected history, research, neurologic and spinal systems.

The presence of dysfunction of the adrenal cortex can be understood in identified in the analyses the shift leukocytosis, increase of residual nitrogen in blood, thrombocytopenia and gipohloremii.


During the treatment of acute insufficiency of the adrenal cortex the main force aimed at replacing dysfunctional cells, restore the metabolism and sodium-potassium balance, suppression of existing infection-irritant and increase in pressure.

All this is done by entering the body through injections and IVS regenerating substances. Such substances are

  • hydrocortisone, dosage which sways from 125 to 500 mg
  • prednisone, used in doses of 60-120 mg
  • a mixture of 5 percent glucose solution and isotonic solution of sodium chloride 2-5 ml
  • a solution of 5 percent ascorbic acid.

After lowering blood pressure to put, administered norepinephrine or mezatona, which are the hormones of the adrenal glands and restore their normal operation. During treatment the dose of hormones is reduced, and at the time of recovery they feed into the body by artificial means is terminated.

When the treatment is prescribed a large number of antibiotics, especially if recurrent disease is meningococcal septicaemia.

We must remember that during the treatment introduced into the body in many different liquids, which as a result can lead to more swelling on the body and organs. Because it is important that monitoring of patients was constant, and in the case of suspected swelling should stop or replace the submission of any solution that has become an irritant.

With the identification and treatment of the syndrome Waterhouse-Friderichsen do not delay, because the provision of untimely care can lead to death. Therefore, in the most minor symptoms should immediately turning to specialists in the medical facility.