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Short Stature Dwarfism

  1. Symptoms
  2. Reasons
  3. Diagnosis
  4. Treatment

Short stature (Dwarfism, Pituitary dwarfism)

this syndrome, which is caused by diseases of both endocrine and endocrinolo character. This disease is very rare and it is characterized by a delay of physical development and characteristics growth that is due to problems with the secretion of somatotropin (growth hormone). Dwarfism in Greek is translated as dwarf.


A symptom of dwarfism is the growth of men less than 130 cm, and in women less than 120 cm in children who are healthy, family short stature can be perceived as physical development.

Characterized by a strong delay in growth and development relative to the average for a certain age, and it may be a decrease in the level of growth and body mass. With the birth of such children can have quite normal levels, but they can clearly keep up with peers. In some forms of dwarfism in children can be seen in the first year of life, but most often it is seen with 24.

I suffer from dwarfism proportions more like a baby. The skin may be pale, dry, as determined by complete or partial lack of function of the parathyroid glands. Those who did not receive proper treatment, may sooner begin to aging skin, wrinkles. Adipose tissue is also poorly developed, can be diagnosed excess fat deposition on the chest, thighs, stomach. Also poorly developed muscular system. There is often a lack of secondary body hair. Also essential feature is a slow ossification of the skeleton. It can be noted and late replacement of deciduous teeth root.

Loss of gonadotropic function of the pituitary gland can manifest symptoms of lack of sexual development. Suffering from dwarfism, male usually have small size penis, underdeveloped scrotum, absence of secondary sexual characteristics. Mental development may be normal with certain juvenile traits. In the case of the neurological examination to detect signs of organic lesions of the nervous system. Also often reduce the size of internal organs, appears

, bradycardia. Can occur secondary gipokortitsizm.

Internal organs have a reduced size. Often, when a problem like dwarfism, it’s symptoms of muffled heart sounds, hypotension, functional noises in different sites.


Among the reasons for the development of such diseases as pituitary dwarfism, stands defeat of the pituitary gland (various injuries, tumors, infectious and toxic damage), and violation of the regulation of pituitary function relative to the hypothalamus.

Play the role of some genetic factors, traumatic, neoplastic, toxic and infectious diseases intermediate-pituitary area.

A reduction or complete loss of somatotropic function of the pituitary gland, biologically inactive growth hormones or sensitivity towards him peripheral tissues.

Many forms of pituitary dwarfism are genetic diseases. The most common is dwarfism. You can meet patients who have affected Central nervous system due to lack of oxygen and injuries. Often this occurs in the case of a multiple pregnancy. Factors that contribute to impaired physical development, may be in the wrong, defective the sake of negative environmental factors.


Stunted growth and obvious short stature is defined already in the first months of a child’s life, and to a lesser extent during puberty. The result of x-ray examination you may notice a delay of ossification and differentiation of the skeleton. Also, the basal concentration of growth hormone in blood serum can be reduced or reply to the norm, the introduction of arginine or insulin does not increase the secretion of growth hormone, as happens in the normal case. Sometimes there is even short-term and barely noticeable improvement in the level of its secretion.


The treatment of dwarfism is hormone replacement therapy. Sometimes therapy, sexual and thyroid hormones. It is also necessary to cure the underlying disease which was the cause of dwarfism.

The main pathogenetic method of treatment of dwarfism is the excretion of human growth hormone. A very important method admits the use of anabolic steroids.

Patients who have clinical manifestations of hypothyroidism need to take thyroid hormones. To stimulate sexual development after the growth zones are closed, use the sex hormones for men human chorionic gonadotropin and the testosterone-containing drugs, and in the case of the pituitary gland adrenal cortex glucocorticoids for women is estrogen, as well as preparations female body.

In that case, if the Central nervous system is violated, the assigned vascular equipment. Sometimes it is dehydration therapy, which has biodegradable properties.

In the treatment of pituitary dwarfism is very important to follow the main rules of substitution therapy, which should be very close in relation to the physiological conditions the secretion of growth hormone. Appointed complex therapy for General strengthening of the body, proper nutrition, intake of vitamins A and D, preparations that contain zinc, calcium, phosphorus. Experts advise to follow a diet that contains a lot of vitamins and protein.

Future forecast for life in the case of genetic forms of dwarfism is favourable, in the case of brain lesions determined by the underlying disease.